CLCNKA Antibody

• Background:

  CLCNKA is a member of the CLC family of voltage-gated chloride channels. It is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  1187

• Swiss Prot:

  P51800

• Accession Number:

  NP_004061

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLCNKA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10409 - Fetal Liver Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CLCNKA antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  75 kDa

• Applications Notes:

  CLCNKA antibody can be used for detection of CLCNKA by ELISA at 1:62500. CLCNKA antibody can be used for detection of CLCNKA by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CLCNKA

• NCBI Official Name:

  Chloride channel, voltage-sensitive Ka

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kramer, B.K., (2008) Nat Clin Pract Nephrol 4 (1), 38-46.

• Other Product Names:

  CLCNKA, CLCK1, ClC-K1, MGC61490, hClC-Ka

• Tested Applications:

  ELISA, WB

• Protein ID:

  112382220

• Physical Properties:

  Liquid