PARP6 Antibody

• Background:

  Poly (ADP-ribose) polymerases (PARPs) constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain. They are involved in DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells.

• NCBI Gene ID:

  56965

• Swiss Prot:

  Q2NL67

• Accession Number:

  NP_064599

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PARP6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1224 - Daudi Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PARP6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  59 kDa

• Applications Notes:

  PARP6 antibody can be used for detection of PARP6 by ELISA at 1:312500. PARP6 antibody can be used for detection of PARP6 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  PARP6

• NCBI Official Name:

  Poly (ADP-ribose) polymerase family, member 6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ota, T., et al., (2004) Nat. Genet. 36 (1), 40-45.

• Other Product Names:

  PARP6, ARTD17, pART17, PARP-6-C, PARP-6-B1

• Tested Applications:

  ELISA, WB

• Protein ID:

  94536838

• Physical Properties:

  Liquid