PARP4 Antibody

• Background:

  This gene encodes poly (ADP-ribosyl) transferase-like 1 protein, which is capable of catalyzing a poly (ADP-ribosyl) ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.

• NCBI Gene ID:

  143

• Swiss Prot:

  Q9UKK3

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PARP4 (NP_006428.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 193kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  PARP4

• Positive Control 2:

  HepG2

• Positive Control 3:

  Mouse heart

• Positive Control 4:

  Rat heart

• NCBI Official Name:

  Poly (ADP-ribose) polymerase family member 4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ADPRTL1, ARTD4, PARP-4, PARPL, PH5P, VAULT3, VPARP, VWA5C, p193, protein mono-ADP-ribosyltransferase PARP4, 193 kDa vault protein, ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) -like 1, ADP-ribosyltransferase diphtheria toxin-like 4, H5 proline-rich, I-alpha-I-related, PARP-related, PARP-related/IalphaI-related H5/proline-rich, poly [ADP-ribose] polymerase 4, poly (ADP-ribose) synthetase, poly (ADP-ribosyl) transferase-like 1, vault poly (ADP-ribose) polymerase, vault protein, 193-kDa, von Willebrand factor A domain containing 5C

• Tested Applications:

  WB

• Physical Properties:

  Liquid