PARP2 Antibody

• Background:

  PARP2 contains a catalytic domain and is capable of catalyzing a poly (ADP-ribosyl) ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of protein.

• NCBI Gene ID:

  10038

• Swiss Prot:

  Q9UGN5

• Accession Number:

  NP_005475

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PARP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1207 - Raji Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PARP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  61 kDa

• Applications Notes:

  PARP2 antibody can be used for detection of PARP2 by ELISA at 1:62500. PARP2 antibody can be used for detection of PARP2 by western blot at 1.6 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  PARP2

• NCBI Official Name:

  Poly (ADP-ribose) polymerase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Malanga, M. et al., (2004) J. Biol. Chem. 279 (7), 5244-5248.

• Other Product Names:

  PARP2, ARTD2, ADPRT2, PARP-2, ADPRTL2, ADPRTL3, pADPRT-2

• Tested Applications:

  ELISA, WB

• Protein ID:

  110825961

• Physical Properties:

  Liquid