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NR4A1 Antibody

CAT: 0223-27-450Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-450Size:100 µL
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Background
NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis.
NCBI Gene ID
3164
Swiss Prot
P22736
Accession Number
NP_775180
Host
Rabbit
Reactivity
Human, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR4A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NR4A1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
66 kDa
Applications Notes
NR4A1 antibody can be used for detection of NR4A1 by ELISA at 1:312500. NR4A1 antibody can be used for detection of NR4A1 by western blot at 1.45 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
NR4A1
NCBI Official Name
Nuclear receptor subfamily 4, group A, member 1
NCBI Organism
Homo sapiens
Background Reference 01
Lu, L., et al., (2004) J. Clin. Endocrinol. Metab. 89 (8), 4113-4118.
Other Product Names
NR4A1, HMR, N10, TR3, NP10, GFRP1, NAK-1, NGFIB, NUR77
Tested Applications
ELISA, WB
Protein ID
27894344
Physical Properties
Liquid

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