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NR4A2 Antibody

CAT: 0223-27-682Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-682Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NR4A2 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. The protein may act as a transcription factor. Mutations in NR4A2 gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of NR4A2 gene may be associated with rheumatoid arthritis.This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full length nature has not been determined.
NCBI Gene ID
4929
Swiss Prot
P43354
Accession Number
NP_006177
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish, Drosophila
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR4A2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NR4A2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
66 kDa, 64 kDa, 68 kDa, 64 kDa, 65 kDa, 60 kDa, 68 kDa, 70 kDa
Applications Notes
NR4A2 antibody can be used for detection of NR4A2 by ELISA at 1:62500. NR4A2 antibody can be used for detection of NR4A2 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
NR4A2
NCBI Official Name
Nuclear receptor subfamily 4, group A, member 2
NCBI Organism
Homo sapiens
Background Reference 01
Holla, V.R., (2006) J. Biol. Chem. 281 (5), 2676-2682.
Other Product Names
NR4A2, HZF-3, NOT, NURR1, RNR1, TINUR
Tested Applications
ELISA, WB
Protein ID
5453822
Physical Properties
Liquid

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