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NR4A3 Antibody

CAT: 0223-58-224Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-224Size:400 µL
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Background
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE) . Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15) . Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
8013
Swiss Prot
Q92570
Accession Number
Q92570
Host
Rabbit
Reactivity
Human
Immunogen
This NR4A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 553-582 amino acids from the C-terminal region of human NR4A3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
68 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NR4A3
NCBI Official Name
Nuclear receptor subfamily 4 group A member 3
NCBI Organism
Homo sapiens
Background Reference 01
Novak, G., et al. Genes Brain Behav. 9 (8) :910-917 (2010)
Background Reference 02
Zhao, Y., et al. Circ. Res. 107 (4) :501-511 (2010)
Background Reference 03
Borup, R., et al. Endocr. Relat. Cancer 17 (3) :691-708 (2010)
Background Reference 04
Thompson, J., et al. Eur. J. Immunol. 40 (7) :2041-2049 (2010)
Other Product Names
Nuclear receptor subfamily 4 group A member 3, Mitogen-induced nuclear orphan receptor, Neuron-derived orphan receptor 1, Nuclear hormone receptor NOR-1, NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Tested Applications
WB
Protein ID
90110039
Physical Properties
Liquid

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