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PDE6A Polyclonal Antibody

CAT: 0866-RD267927A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD267927A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the cyclic-GMP (cGMP) -specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
Description
This is a PDE6A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PDE6A, CGPR-A, PDEA, RP43
Gene ID
5145
Swiss Prot
P16499
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PDE6A (NP_000431.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
99 kDa
Observed Molecular Weight
120 kDa
Host or Source
Rabbit
Isotype
IgG

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