PDE6C Antibody

• Background:

  PDE6C is the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa.

• NCBI Gene ID:

  5146

• Swiss Prot:

  P51160

• Accession Number:

  P51160

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This PDE6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 amino acids from the Central region of human PDE6C.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  99 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For IHC-P starting dilution is: 1:50~100

• Symbol:

  PDE6C

• NCBI Official Name:

  Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Muradov, H., et al. J. Biol. Chem. 284 (47) :32662-32669 (2009) Chang, B., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (46) :19581-19586 (2009) Thiadens, A.A., et al. Am. J. Hum. Genet. 85 (2) :240-247 (2009)

• Other Product Names:

  Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', cGMP phosphodiesterase 6C, PDE6C, PDEA2

• Tested Applications:

  IHC-P

• Protein ID:

  90111861

• Physical Properties:

  Liquid