CD1B Antibody

CAT: 0223-22-306Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-22-306Size:100 µL
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Background
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
NCBI Gene ID
910
Swiss Prot
P29016
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 18-303 of human CD1B (NP_001755.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Affinity purification
Positive Control
NCI-H125
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 47kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CD1B
NCBI Official Name
CD1b molecule
NCBI Organism
Homo sapiens
Other Product Names
T-cell surface glycoprotein CD1b, CD1b, CD1B
Tested Applications
WB
Physical Properties
Liquid

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