FBXL5 Antibody

• Background:

  This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus.

• NCBI Gene ID:

  26234

• Swiss Prot:

  Q9UKA1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human FBXL5 (NP_036293.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 79kDa

• Fragment:

  IgG

• Symbol:

  FBXL5

• Positive Control 2:

  Mouse eye

• Positive Control 3:

  Mouse brain

• Positive Control 4:

  Mouse lung

• Positive Control 5:

  Rat testis

• Positive Control 6:

  Rat lung

• NCBI Official Name:

  F-box and leucine-rich repeat protein 5

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  FBXL5, FBL4, FBL5, FLR1

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid