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FBXL8 Antibody

CAT: 0223-59-525Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-525Size:400 µL
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Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein.
NCBI Gene ID
55336
Swiss Prot
Q96CD0
Accession Number
Q96CD0
Host
Rabbit
Reactivity
Human
Immunogen
This FBXL8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-83 amino acids from the N-terminal region of human FBXL8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FBXL8
NCBI Official Name
F-box/LRR-repeat protein 8
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 03
Lievens, S., et al. J. Proteome Res. 8 (2) :877-886 (2009)
Background Reference 04
Winston, J.T., et al. Curr. Biol. 9 (20) :1180-1182 (1999)
Other Product Names
F-box/LRR-repeat protein 8, F-box and leucine-rich repeat protein 8, F-box protein FBL8, FBXL8, FBL8
Tested Applications
WB
Protein ID
38257737
Physical Properties
Liquid

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