FBXL3 Antibody

• Background:

  This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.

• NCBI Gene ID:

  50789

• Swiss Prot:

  Q8C4V4

• Accession Number:

  NP_056637.1

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  FBXL3 antibody was raised against a peptide sequence around aa.1~5 (M-K-R-G-G) derived from mouse FBXL3 .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  49 kDa

• Specificity:

  This antibody detects endogenous levels of total FBXL3 protein.

• Applications Notes:

  Western Blot: 1:500~1:1000

• Symbol:

  Fbxl3

• NCBI Official Name:

  F-box and leucine-rich repeat protein 3

• NCBI Organism:

  This antibody was raised against a peptide sequence around aa.1~5 (M-K-R-G-G) derived from mouse FBXL3

• Background Reference 01:

  "Winston J. T., et al. (1999) Curr. Biol. 9:1180-1182. Carninci P. et al. (2005) Science 309:1559-1563. The MGC Project Team, (2004) Genome Res. 14:2121-2127.

• Other Product Names:

  FBK, Ovtm, Fbl3a, Fbxl3a, Play68, AU041772, AW212966, FBK, FBXL3

• Tested Applications:

  WB

• Protein ID:

  29789070

• Physical Properties:

  Liquid