FBXL7 Antibody

FBXL7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats.

23194

Q9UJT9

NP_036436

Human, Mouse, Rat

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FBXL7.

Unconjugated

Primary Antibodies

Apoptosis, Homeostasis

Antibody is purified by protein A chromatography method.

Cat. No. 1211 - HepG2 Cell Lysate

Batch dependent

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

None

Blue Ice

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FBXL7 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

54 kDa

FBXL7 antibody can be used for detection of FBXL7 by ELISA at 1:312500. FBXL7 antibody can be used for detection of FBXL7 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

FBXL7

F-box and leucine-rich repeat protein 7

Homo sapiens

Venables, J.P., (2005) Hum. Mol. Genet. 14 (16), 2289-2303.

FBXL7, FBL6, FBL7

ELISA, WB, IHC

6912466