SDHA Antibody

• Background:

  This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  6389

• Swiss Prot:

  P31040

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 385-664 of human SDHA (NP_004159.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 70kDa

• Fragment:

  IgG

• Symbol:

  SDHA

• Positive Control 2:

  U-251MG

• Positive Control 3:

  PC-3

• Positive Control 4:

  MCF7

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Mouse stomach

• NCBI Official Name:

  Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Flavoprotein subunit of complex II, Fp, SDHA, SDH2, SDHF

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid