PSMD11 Antibody

CAT: 0223-15-977Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-15-977Size:100 µL
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Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene.
NCBI Gene ID
5717
Swiss Prot
O00231
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 253-422 of human PSMD11 (NP_002806.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
H460
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 47kDa
Fragment
IgG
Symbol
PSMD11
Positive Control 2
BxPC-3
Positive Control 3
293T
Positive Control 4
LO2
Positive Control 5
Mouse brain
Positive Control 6
Mouse heart
NCBI Official Name
Proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
NCBI Organism
Homo sapiens
Other Product Names
PSMD11, MGC3844, S9, p44.5, Rpn6
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

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