PSMD14 Antibody

• Background:

  PSMD14 is a component of the 26S proteasome, a multiprotein complex that degrades proteins targeted for destruction by the ubiquitin pathway (Spataro et al., 1997 [PubMed 9374539]) .

• NCBI Gene ID:

  10213

• Swiss Prot:

  O00487

• Accession Number:

  O00487

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PSMD14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from the C-terminal region of human PSMD14.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  35 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PSMD14

• NCBI Official Name:

  26S proteasome non-ATPase regulatory subunit 14

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Byrne, A., et al. Exp. Cell Res. 316 (2) :258-271 (2010)

• Background Reference 02:

  Ma, Z., et al. Pediatr Int 51 (5) :732-735 (2009)

• Background Reference 03:

  Cooper, E.M., et al. EMBO J. 28 (6) :621-631 (2009)

• Background Reference 04:

  Koulich, E., et al. Mol. Biol. Cell 19 (3) :1072-1082 (2008)

• Other Product Names:

  26S proteasome non-ATPase regulatory subunit 14, 3419-, 26S proteasome regulatory subunit RPN11, 26S proteasome-associated PAD1 homolog 1, PSMD14, POH1

• Tested Applications:

  WB

• Physical Properties:

  Liquid