11S(12R)-EET

11S(12R)-EET

• CAS Number: 123931-40-8
• UNSPSC Description: 11S(12R)-EET is a dominant enantiomer of epoxytrienoic acid (EET) that is metabolized at a higher rate in rat organs. It shows enantiomeric-dependent reaction selectivity in hydration, especially in the case of 11,12-EET, where water addition is non-regioselective, while in 8,9-EET, water addition occurs mainly at the C9 position. In addition, 11S(12R)-EET generates diol products with specific stereochemistry through enzymatic hydration reactions, which are affected by the selective recognition of epoxidases, reaction conversion rates, and substrate binding parameters[1].
• Target Antigen: Others
• Type: Natural Products
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/11s-12r-eet.html
• Smiles: OC(CCC/C=C\C/C=C\C[C@H]1[C@H](O1)C/C=C\CCCCC)=O
• Molecular Weight: 320.47
• References & Citations: [1]Zeldin D C, et al. Metabolism of epoxyeicosatrienoic acids by cytosolic epoxide hydrolase: substrate structural determinants of asymmetric catalysis[J]. Archives of biochemistry and biophysics, 1995, 316(1): 443-451.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported