CDK2-IN-23

• Target:

  CDK

• Related Pathways:

  Cell Cycle/Checkpoint

• Bioactivity:

  CDK2-IN-23 (Compound 17), a selective and highly potent inhibitor of CDK2 (IC 50 = 0.29 nM), demonstrates pharmacodynamic inhibition of CDK2 in CCNE1-amplified mouse models. This compound is utilized in cancer research [1].

• Smiles:

  C(F)(F)(F)C=1C(=NC(NC2CCN(S(=O)(=O)C3CC3)CC2)=NC1)C4=CN(CC(C)(C)O)N=C4

• Molecular Formula:

  C20H27F3N6O3S

• Molecular Weight:

  488.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2488073-20-5