TP-680

• Description:

  TP-680 is a cholecystokinin receptor antagonist. TP-680 binds 1510 times more strongly to rat pancreatic CCKA receptors (IC50=1.2 nM) than to rat brain CCKB receptors (IC50=1812.5 nM) . TP-680 can be used in the study of gastrointestinal diseases[1].

• UNSPSC:

  12352005

• Target:

  Cholecystokinin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/tp-680.html

• Smiles:

  O=C(O)C1=CC=CN=C1SC[C@@H](C(N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)=O)NC(C5=CC6=C(C=CC=C6)N5)=O

• Molecular Formula:

  C35H33N5O4S

• Molecular Weight:

  619.73

• References & Citations:

  [1]Akiyama T, et al. Pharmacological profile of TP-680, a new cholecystokininA receptor antagonist[J]. British journal of pharmacology, 1996, 117 (7) : 1558.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CCKAR; CCKBR

• CAS Number:

  [176915-07-4]