TP-680

CAT: 0804-HY-119127Size: 1 EachDry Ice: NoHazardous: No

CAT#:0804-HY-119127Size:1 Each

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Description

TP-680 is a cholecystokinin receptor antagonist. TP-680 binds 1510 times more strongly to rat pancreatic CCKA receptors (IC50=1.2 nM) than to rat brain CCKB receptors (IC50=1812.5 nM) . TP-680 can be used in the study of gastrointestinal diseases[1].

CAS Number

[176915-07-4]

UNSPSC

12352005

Target

Cholecystokinin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/tp-680.html

Smiles

O=C(O)C1=CC=CN=C1SC[C@@H](C(N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)=O)NC(C5=CC6=C(C=CC=C6)N5)=O

Molecular Formula

C35H33N5O4S

Molecular Weight

619.73

References & Citations

[1]Akiyama T, et al. Pharmacological profile of TP-680, a new cholecystokininA receptor antagonist[J]. British journal of pharmacology, 1996, 117 (7) : 1558.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CCKAR; CCKBR

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TP-680

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