EA-89

CAT: 0804-HY-170314Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-170314Size:1 Each
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Description
EA-89 is a potent and selective BRD9 inhibitor with antitumor activity. EA-89 is a Ligand for Target Protein for PROTAC. EA-89 can be used to synthesize PROTAC QA-68 (HY-150797) [1].
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ea-89.html
Smiles
CCCN1C=C(C2=CC=C(N(CC3CCNCC3)C=C4C)C4=C2)C5=C(C=C(S5)C(NC6CCS(CC6)(=O)=O)=O)C1=O
Molecular Formula
C31H38N4O4S2
Molecular Weight
594.79
References & Citations
[1]Weisberg E, et al. BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma. Blood Cancer J. 2022 Jul 19;12 (7) :110.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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