EA-89

• Description :

  EA-89 is a potent and selective BRD9 inhibitor with antitumor activity. EA-89 is a Ligand for Target Protein for PROTAC. EA-89 can be used to synthesize PROTAC QA-68 (HY-150797) [1].

• UNSPSC :

  12352005

• Target :

  Ligands for Target Protein for PROTAC

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/ea-89.html

• Smiles :

  CCCN1C=C(C2=CC=C(N(CC3CCNCC3)C=C4C)C4=C2)C5=C(C=C(S5)C(NC6CCS(CC6)(=O)=O)=O)C1=O

• Molecular Formula :

  C31H38N4O4S2

• Molecular Weight :

  594.79

• References & Citations :

  [1]Weisberg E, et al. BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma. Blood Cancer J. 2022 Jul 19;12 (7) :110.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported