Ginsenoside Rk3

Ginsenoside Rk3

• CAS Number: 364779-15-7
• UNSPSC Description: Ginsenoside Rk3 is present in the roots Panax ginseng herbs. Ginsenoside Rk3 significantly inhibits TNF-α-induced NF-κB transcriptional activity, with an IC50 of 14.24±1.30 μM in HepG2 cells.
• Target Antigen: NF-κB
• Type: Natural Products
• Related Pathways: NF-κB
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/Ginsenoside-Rk3.html
• Purity: 98.85
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: C[C@@]([C@@]12C)(C[C@H](O[C@]([C@@H]([C@@H](O)[C@@H]3O)O)([H])O[C@@H]3CO)[C@@]4([H])C5(C)C)[C@@](C[C@@H](O)[C@]1([H])[C@@H](C(CC/C=C(C)/C)=C)CC2)([H])[C@]4(CC[C@@H]5O)C
• Molecular Weight: 620.86
• References & Citations: [1]Cho K, et al. Inhibition of TNF-α-Mediated NF-κB Transcriptional Activity by Dammarane-Type Ginsenosidesfrom Steamed Flower Buds of Panax ginseng in HepG2 and SK-Hep1 Cells. Biomol Ther (Seoul). 2014 Jan;22(1):55-61.|[2]Duan Z, et al. Anticancer effects of ginsenoside Rk3 on non-small cell lung cancer cells: in vitro and in vivo. Food Funct. 2017 Oct 18;8(10):3723-3736.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, protect from light)
• Clinical Information: No Development Reported