Ginsenoside Rb1

• Description :

  Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with an IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65 .

• CAS Number :

  [41753-43-9]

• Product Name Alternative :

  Gypenoside III

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Autophagy; HSV; IRAK; Mitophagy; Na+/K+ ATPase; NF-κB; Pregnane X Receptor (PXR)

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Autophagy; Immunology/Inflammation; Membrane Transporter/Ion Channel; NF-κB; Vitamin D Related/Nuclear Receptor

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Inflammation/Immunology; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Ginsenoside-Rb1.html

• Concentration :

  10mM

• Purity :

  99.75

• Solubility :

  DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 33.33 mg/mL

• Smiles :

  C[C@@]([C@@]12C)(CC[C@@]3([H])C4(C)C)[C@@](C[C@@H](O)[C@]1([H])[C@]([C@@](CC/C=C(C)/C)(C)O[C@@H]([C@@H]([C@@H](O)[C@@H]5O)O)O[C@@H]5CO[C@@H]([C@@H]([C@@H](O)[C@@H]6O)O)O[C@@H]6CO)([H])CC2)([H])[C@]3(CC[C@@H]4O[C@@](O[C@H](CO)[C@@H](O)[C@@H]7O)([H])[C@@H]7O[C@]([C@@H]([C@@H](O)[C@@H]8O)O)([H])O[C@@H]8CO)C

• Molecular Formula :

  C54H92O23

• Molecular Weight :

  1109.29

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  ++

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  HSV-1; IRAK1; RelA/p65