Ginsenoside Rh2

• Description:

  Ginsenoside Rh2 (20 (S) -Ginsenoside Rh2) induces the activation of caspase-8 and caspase-9. Ginsenoside Rh2 induces cancer cell apoptosis in a multi-path manner.

• Product Name Alternative:

  20 (S) -Ginsenoside Rh2; 20 (S) -Rh2

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Apoptosis; Caspase; Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Apoptosis; Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Ginsenoside-Rh2.html

• Purity:

  98.87

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O[C@]([C@@H]([C@@H](O)[C@@H]4O)O)([H])O[C@@H]4CO)C)(CC[C@@]2([H])C3(C)C)[C@]5([C@@]1([H])[C@]([C@@](C)(O)CC/C=C(C)/C)([H])CC5)C

• Molecular Formula:

  C36H62O8

• Molecular Weight:

  622.87

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Guo XX, et al. p53-dependent Fas expression is critical for Ginsenoside Rh2 triggered caspase-8 activation in HeLa cells. Protein Cell. 2014 Mar;5 (3) :224-34.|[2]Wang M, et al. Ginsenoside Rh2 enhances the antitumor immunological response of a melanoma mice model. Oncol Lett. 2017 Feb;13 (2) :681-685.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  Caspase 8; Caspase 9

• CAS Number:

  [78214-33-2]