UCB-9260

CAT: 0804-HY-133122-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-133122-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
UCB-9260, an orally active compound, inhibits TNF signaling by stabilising an asymmetric form of the trimer. UCB-9260 is selective for TNF over other superfamily members, and binds TNF with a similar Kd of 13 nM[1].
CAS Number
[1515888-53-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/ucb-9260.html
Purity
98.38
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC(C1=CC=NC=C1)C2=NC3=CC=C(C4=CN(C)N=C4)C=C3N2CC5=CC(C)=CC=C5C
Molecular Formula
C26H25N5O
Molecular Weight
423.51
Precautions
H302, H315, H319
References & Citations
[1]O'Connell J, et al.Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer.Nat Commun. 2019 Dec 19;10 (1) :5795.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-19443-01UCB-35440
HY-147045-01UCB-5307
HY-136873-01UCB-J
HY-120547-01UCB-11056
HY-156454-01UCB-6876
HY-136873A(Rac) -UCB-J
HY-105140CPA 926

Alternative Products

CatalogName
C09225-01UCB-9260
A22416-10UCB-9260 10mg
A22416-1UCB-9260 1mg
A22416-25UCB-9260 25mg
A22416-50UCB-9260 50mg
A22416-100UCB-9260 100mg
A22416-5UCB-9260 5mg
M35511-01UCB-5307
T23492-01UCB 35625
MBS5799617-01UCB-J

Popular Products