CPA 926

CAT: 0804-HY-105140Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-105140Size:1 Each
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Description
CPA 926 is a prodrug of Esculetin (HY-N0284) and is orally active. CPA 926 can inhibit the production of MMP in cartilage explants. CPA 926 can be used for the research of inflammation, such as experimental osteoarthritis[1].
CAS Number
[169673-60-3]
UNSPSC
12352005
Target
MMP
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
OC1=C(C=C2C(OC(C=C2)=O)=C1)O[C@H]3[C@@H]([C@H]([C@H](O)[C@@H](CO)O3)O)NC(C)=O
Molecular Formula
C17H19NO9
Molecular Weight
381.33
References & Citations
[1]Yamada H, et al. Esculetin (dihydroxycoumarin) inhibits the production of matrix metalloproteinases in cartilage explants, and oral administration of its prodrug, CPA-926, suppresses cartilage destruction in rabbit experimental osteoarthritis. J Rheumatol. 1999 Mar;26 (3) :654-62.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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