(Rac) -UCB-J

CAT: 0804-HY-136873ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-136873ASize:1 Each
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Description
(Rac) -UCB-J (Compound 23) is a ligand for synaptic vesicle protein 2A (SV2A), with a pIC50 value of 8.2. (Rac) -UCB-J can be used as a PET tracer for SV2A to assist in the diagnosis of epilepsy research[1].
CAS Number
[1604786-87-9]
UNSPSC
12352005
Target
Synaptic Vesicle Proteins
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C1CC(C2=CC(F)=C(C(F)=C2)F)CN1CC3=CC=NC=C3C
Molecular Formula
C17H15F3N2O
Molecular Weight
320.31
References & Citations
[1]Joël Mercier, et al. Discovery of heterocyclic nonacetamide synaptic vesicle protein 2A (SV2A) ligands with single-digit nanomolar potency: opening avenues towards the first SV2A positron emission tomography (PET) ligands. ChemMedChem. 2014 Apr;9 (4) :693-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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