(Rac) -UCB-J

• Description :

  (Rac) -UCB-J (Compound 23) is a ligand for synaptic vesicle protein 2A (SV2A), with a pIC50 value of 8.2. (Rac) -UCB-J can be used as a PET tracer for SV2A to assist in the diagnosis of epilepsy research[1].

• CAS Number :

  [1604786-87-9]

• UNSPSC :

  12352005

• Target :

  Synaptic Vesicle Proteins

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Smiles :

  O=C1CC(C2=CC(F)=C(C(F)=C2)F)CN1CC3=CC=NC=C3C

• Molecular Formula :

  C17H15F3N2O

• Molecular Weight :

  320.31

• References & Citations :

  [1]Joël Mercier, et al. Discovery of heterocyclic nonacetamide synaptic vesicle protein 2A (SV2A) ligands with single-digit nanomolar potency: opening avenues towards the first SV2A positron emission tomography (PET) ligands. ChemMedChem. 2014 Apr;9 (4) :693-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported