Products for Research Use Only
RegisterLogin

1-Methyladenosine

CAT: 0804-HY-113081-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-113081-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
1-Methyladenosine is an RNA modification that can serve as a tumor marker, with elevated levels in the body associated with cancer development. Following 1-methyladenosine methylation, upregulation of PPARδ expression regulates cholesterol metabolism and activates Hedgehog signaling pathway, driving liver tumorigenesis[1][2][3].
CAS Number
15763-06-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Hedgehog; PPAR
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Stem Cell/Wnt; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-Methyladenosine.html
Purity
99.92
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=CN(C)C3=N)=C3N=C2)O1
Molecular Formula
C11H15N5O4
Molecular Weight
281.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Hauenschild R, et al. The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent. Nucleic Acids Res. 2015 Nov 16;43 (20) :9950-64.|[2]Banys K, et al. Effect of Genistein Supplementation on the Progression of Neoplasms and the Level of the Modified Nucleosides in Rats With Mammary Cancer. In Vivo. 2021 Jul-Aug;35 (4) :2059-2072. |[3]Wang Y, et al. N 1-methyladenosine methylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism[J]. Nature communications, 2021, 12 (1) : 6314.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite; PPARγ

Related Products

CatalogName
HY-152697-012-Methyladenosine
HY-1525994’-Methyladenosine
HY-N0086-01N6-Methyladenosine
HY-1522968-Methyladenosine
HY-N0086S3N6-Methyladenosine-13C3
HY-125371-012'-C-Methyladenosine
HY-N0086R-01N6-Methyladenosine (Standard)
HY-N0086S-01N6-Methyladenosine-d3
HY-W011552-012'-O-Methyladenosine
HY-N0086S1N6-Methyladenosine-13C

Alternative Products

CatalogName
sc-216121D1-Methyladenosine
abx1881351-Methyladenosine Hydriodide
A18841-1001-Methyladenosine 100mg
A18841-251-Methyladenosine 25mg
T203278-011-Methyladenosine-d
T200437-011-Methyladenosine-d3
A18841-5001-Methyladenosine 500mg
A18841-501-Methyladenosine 50mg
BA4342-12-Methyladenosine
NM03697-01N1-Methyladenosine

Popular Products