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N6-Methyladenosine-d3

CAT: 0804-HY-N0086S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0086S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
N6-Methyladenosine-d3 (6-Methyladenosine-d3; N-Methyladenosine-d3) is a deuterium labeled N6-Methyladenosine. N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
CAS Number
139896-43-8
Product Name Alternative
6-Methyladenosine-d3; N-Methyladenosine-d3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Influenza Virus; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Applications
COVID-19-anti-virus
Field of Research
Infection
Purity
99.97
Solubility
DMSO : 31 mg/mL (ultrasonic; warming)
Smiles
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=CN=C3NC([2H])([2H])[2H])=C3N=C2)O1
Molecular Formula
C11H12D3N5O4
Molecular Weight
284.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-246.|[2]Wang X, et al. N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 2;505 (7481) :117-20.|[3]Li Y, et al. Genome-wide detection of high abundance N6-methyladenosine sites by microarray. RNA. 2015 Aug;21 (8) :1511-8.|[4]Dang W, et al. N6-Methyladenosine and Viral Infection. Front Microbiol. 2019 Mar 5;10:417.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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