N6-Methyladenosine-d3

N6-Methyladenosine-d3

• CAS Number: 139896-43-8
• UNSPSC Description: N6-Methyladenosine-d3 (6-Methyladenosine-d3; N-Methyladenosine-d3) is a deuterium labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
• Target Antigen: Endogenous Metabolite; Influenza Virus; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Anti-infection;Metabolic Enzyme/Protease;Others
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Purity: 99.97
• Solubility: DMSO : 31 mg/mL (ultrasonic;warming)
• Smiles: OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=CN=C3NC([2H])([2H])[2H])=C3N=C2)O1
• Molecular Weight: 284.29
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246.|[2]Wang X, et al. N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 2;505(7481):117-20.|[3]Li Y, et al. Genome-wide detection of high abundance N6-methyladenosine sites by microarray. RNA. 2015 Aug;21(8):1511-8.|[4]Dang W, et al. N6-Methyladenosine and Viral Infection. Front Microbiol. 2019 Mar 5;10:417.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
• Clinical Information: No Development Reported