2'-O-Methyladenosine

• Description :

  2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities [1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Endogenous Metabolite

• Type :

  Natural Products

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/2-o-methyladenosine.html

• Purity :

  99.94

• Solubility :

  DMSO : 66.67 mg/mL (ultrasonic)

• Smiles :

  O[C@H]1[C@@H](OC)[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1CO

• Molecular Formula :

  C11H15N5O4

• Molecular Weight :

  281.27

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Hirschhorn R, et al. Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency. Pediatr Res. 1982 May;16 (5) :362-9.|[2]Yamada T, et al. Naturally occurring 2'-O-methylpurine nucleosides with hypotensive properties. Cell Mol Life Sci. 1998 Feb;54 (2) :125-8.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  Human Endogenous Metabolite

• CAS Number :

  [2140-79-6]