2'-O-Methyladenosine

• UNSPSC Description:

  2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities [1][2].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/2-o-methyladenosine.html

• Purity:

  99.94

• Solubility:

  DMSO : 66.67 mg/mL (ultrasonic)

• Smiles:

  O[C@H]1[C@@H](OC)[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1CO

• Molecular Weight:

  281.272

• References & Citations:

  [1]Hirschhorn R, et al. Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency. Pediatr Res. 1982 May;16(5):362-9.|[2]Yamada T, et al. Naturally occurring 2'-O-methylpurine nucleosides with hypotensive properties. Cell Mol Life Sci. 1998 Feb;54(2):125-8.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  2140-79-6