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MI 14

CAT: 0804-HY-110248-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-110248-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MI 14 is a selective PI4KIIIβ inhibitor with IC50s of 54 nM, >100 μM, >100 μM for PI4KIIIβ, PI4KIIIα, PI4KIIα, respectively. MI 14 has antiviral activity against HCV 1b, CVB3, HRVM, HVC 2a[1].
CAS Number
1715934-43-2
UNSPSC
12352005
Target
HCV; PI4K
Type
Reference compound
Related Pathways
Anti-infection; PI3K/Akt/mTOR
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mi-14.html
Purity
99.30
Solubility
DMSO : 9.02 mg/mL (ultrasonic; warming)
Smiles
O=C(C)NCCNC1=CC(Cl)=NN2C1=NC(C)=C2C3=CC(S(=O)(N(C)C)=O)=CC=C3
Molecular Formula
C19H23ClN6O3S
Molecular Weight
450.94
References & Citations
[1]Ivana Mejdrová, et al. Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of Action. J Med Chem. 2015 May 14;58 (9) :3767-93.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI4KII; PI4KIIIα; PI4KIIIβ

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