STING agonist-1

• UNSPSC Description:

  STING agonist-1 (G10) is human-specific STING agonist that elicits antiviral activity against emerging Alphaviruses. G10 potently blocks replication of Alphavirus species Venezuelan Equine Encephalitis Virus (VEEV) with IC90 of 24.57 μM[1].

• Target Antigen:

  STING; Virus Protease

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Immunology/Inflammation

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/STING-agonist-1.html

• Purity:

  99.93

• Solubility:

  DMSO : 75 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=CC=C(SCC(N2CC3=C(F)C=CC=C3Cl)=O)C2=C1)NCC4=CC=CO4

• Molecular Weight:

  430.88

• References & Citations:

  [1]Sali TM, et al. Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses. PLoS Pathog. 2015 Dec 8;11(12):e1005324.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  702662-50-8