5 (6) -CFDA

• Description:

  5 (6) -CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes[1][2][3].

• Product Name Alternative:

  5- (6) -Carboxyfluorescein diacetate; CFDA

• UNSPSC:

  12171500

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/5_6_-CFDA.html

• Purity:

  99.31

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC (OC1=CC=C2C (OC3=C (C=CC (OC (C) =O) =C3) C24C5=CC (C (O) =O) =CC=C5C (O4) =O) =C1) =O.CC (OC6=CC=C7C (OC8=C (C=CC (OC (C) =O) =C8) C79C%10=CC=C (C (O) =O) C=C%10C (O9) =O) =C6) =O

• Molecular Formula:

  C25H16O9

• Molecular Weight:

  460.39

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Yang T, et al. A novel nonradioactive CFDA assay to monitor the cellular immune response in myeloid leukemia. Immunobiology. 2013 Apr;218 (4) :548-53.|[2]Card SD, et al. Assessment of fluorescein-based fluorescent dyes for tracing Neotyphodium endophytes in planta. Mycologia. 2013 Jan-Feb;105 (1) :221-9.|[3]Fang X, et al. Bone marrow-derived endothelial progenitor cells are involved in aneurysm repair in rabbits. J Clin Neurosci. 2012 Sep;19 (9) :1283-6.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  124387-19-5