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5-CFDA

CAT: 0804-HY-D0047Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-D0047Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
5-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes[1][2][3].
CAS Number
79955-27-4
Product Name Alternative
5-Carboxyfluorescein diacetate
UNSPSC
12171500
Hazard Statement
H315, H319
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-CFDA.html
Purity
98.22
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1=CC2=C(C3(C4=C(OC5=C3C=CC(OC(C)=O)=C5)C=C(OC(C)=O)C=C4)OC2=O)C=C1)O
Molecular Formula
C25H16O9
Molecular Weight
460.39
Precautions
H315, H319
References & Citations
[1]Yang T, et al. A novel nonradioactive CFDA assay to monitor the cellular immune response in myeloid leukemia. Immunobiology. 2013 Apr;218 (4) :548-53.|[2]Card SD, et al. Assessment of fluorescein-based fluorescent dyes for tracing Neotyphodium endophytes in planta. Mycologia. 2013 Jan-Feb;105 (1) :221-9.|[3]Fang X, et al. Bone marrow-derived endothelial progenitor cells are involved in aneurysm repair in rabbits. J Clin Neurosci. 2012 Sep;19 (9) :1283-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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