FT-1518

• Description :

  FT-1518 is a new generation selective, potent and oral bioavailable mTORC1 and mTORC2 inhibitor, and exhibits antitumor activity.

• UNSPSC :

  12352005

• Target :

  MTOR

• Type :

  Reference compound

• Related Pathways :

  PI3K/Akt/mTOR

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/FT-1518.html

• Purity :

  98.62

• Solubility :

  DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  CCC(N1C2=NC(N3CC4OC(CC4)C3)=NC(C5=NC=C(N)N=C5)=C2N=C1)CC

• Molecular Formula :

  C20H26N8O

• Molecular Weight :

  394.47

• References & Citations :

  [1]Alain C. Mita, et al. Abstract 137: FT-1518, a new generation selective and potent mTORC1 and mTORC2 inhibitor: an in vitro and in vivo profile. Cancer Res 2017;77 (13 Suppl) .

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  MTORC1; mTORC2

• CAS Number :

  [1313026-58-2]