N-1518

CAT:

804-HY-19012

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CAS Number: 93750-14-2
UNSPSC Description: N-1518 is an α and β adrenergic receptor blocker that has competitive antagonism against β1 and α1 receptors, but does not show selectivity for β1 receptors, but shows about 20-fold selectivity for α1 receptors. N-1518 has vasodilatory effects and can be used in the research field of hypertension treatment[1].
Target Antigen: Adrenergic Receptor
Type: Reference compound
Related Pathways: GPCR/G Protein;Neuronal Signaling
Field of Research: Cardiovascular Disease
Assay Protocol: https://www.medchemexpress.com/n-1518.html
Smiles: O=C1NC=C(C2=C1C=CC=C2)OCC(CNC(COC3=C(OC)C=CC=C3)C)O
Molecular Weight: 398.45
References & Citations: [1]T Sugai, et al. [Pharmacological properties of (+/-)-4-[2-hydroxy-3-(3-(2-methoxyphenoxy)-2-propylamino) propoxy]-1 (2H)-isoquinolinone (N-1518), a new combined alpha-and beta-adrenoceptor blocking drug]. Nihon Yakurigaku zasshi. Folia Pharmacologica Japonica 96.3 (1990): 117-127.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-19012	N-1518
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HY-107363-01	FT-1518
HY-107363-05	FT-1518
HY-107363-03	FT-1518
HY-107363-04	FT-1518
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