CPI-1328

• Description :

  CPI-1328 is an EZH2 inhibitor with a Ki value of 63 fM.

• UNSPSC :

  12352005

• Target :

  Histone Methyltransferase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cpi-1328.html

• Solubility :

  10 mM in DMSO

• Smiles :

  ClC1=C2C(O[C@](O2)([C@]3([H])CC[C@H](CC3)N(C)C)C)=C(C4=C1CCN(C4=O)CC5=C(C=C(NC5=O)C)SC)C

• Molecular Formula :

  C28H36ClN3O4S

• Molecular Weight :

  546.12

• References & Citations :

  [1]Stuckey JI, et al. Identification and characterization of second-generation EZH2 inhibitors with extended residence times and improved biological activity. J Biol Chem. 2021 Jan-Jun;296:100349.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  EZH2

• CAS Number :

  [2390367-27-6]