MK-28

• UNSPSC Description:

  MK-28 is a potent and selective PERK activator. MK-28 exhibits remarkable pharmacokinetic properties and high BBB penetration in mice[1].

• Target Antigen:

  PERK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/mk-28.html

• Smiles:

  OC1=CC=C(C=C1O)/C=N/N(C2=NC(C3=CC=CC=C3)=CC(C4=CC=CC=C4)=N2)C

• Molecular Weight:

  396.44

• References & Citations:

  [1]Javier Ganz, et al. A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models. Sci Rep. 2020 Apr 23;10(1):6875.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  864388-65-8