YK-2168

• Description :

  YK-2168 is a differentiated selective inhibitor of CDK9[1].

• CAS Number :

  [2571068-74-9]

• UNSPSC :

  12352005

• Target :

  CDK

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/yk-2168.html

• Purity :

  98.05

• Solubility :

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  ClC1=CN=C(NC(C2CCNCC2)=C3)C3=C1C4=CN(C)N=C4

• Molecular Formula :

  C16H18ClN5

• Molecular Weight :

  315.80

• References & Citations :

  [1]Yingchun Liu, et al. Discovery and preclinical profile of YK-2168, a differentiated selective CDK9 inhibitor in clinical development. Bioorg Med Chem Lett. 2024 Nov 1:112:129941.Yingchun Liu, et al. Discovery and preclinical profile of YK-2168, a differentiated selective CDK9 inhibitor in clinical development. Bioorg Med Chem Lett. 2024 Nov 1:112:129941.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported