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YK-2168

CAT: 0804-HY-162919-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-162919-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YK-2168 is a differentiated selective inhibitor of CDK9[1].
CAS Number
2571068-74-9
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/yk-2168.html
Purity
98.05
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
ClC1=CN=C(NC(C2CCNCC2)=C3)C3=C1C4=CN(C)N=C4
Molecular Formula
C16H18ClN5
Molecular Weight
315.80
References & Citations
[1]Yingchun Liu, et al. Discovery and preclinical profile of YK-2168, a differentiated selective CDK9 inhibitor in clinical development. Bioorg Med Chem Lett. 2024 Nov 1:112:129941.Yingchun Liu, et al. Discovery and preclinical profile of YK-2168, a differentiated selective CDK9 inhibitor in clinical development. Bioorg Med Chem Lett. 2024 Nov 1:112:129941.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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