Products for Research Use Only

NEK7 degrader-2

CAT: 0013-GTR19280759-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19280759-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NEK7degrader-2 (Compound 25) serves as a NEK7 degrader. It demonstrates a dose-dependent ability to degrade NEK7 in macrophages derived from human peripheral blood mononuclear cells, and reduces the release of the pro-inflammatory cytokine IL-1β, induced by NLRP3 inflammasome activation. NEK7degrader-2 is applicable for research into inflammatory diseases.
CAS Number
3037413-54-7
Smiles
O=C1NC (=O) C (N2C (=O) C3=CC=C (C=C3C2C) C4NCCCC4) CC1
Molecular Formula
C19H23N3O3
Molecular Weight
341.41
Notes
For research use only.