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PROTAC USP39 Degrader-1

CAT: 0013-GTR19277122-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19277122-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACUSP39 Degrader-1 (compound USP39_PROTAC_V1) is an efficient and selective degrader of PROTACUSP39. It recruits VHL E3 ligase through a hydroxyproline-containing ligand to form a ternary complex (Kd = 232 nM), thereby inducing the degradation of USP39. This degradation occurs in a VHL-dependent, proteasome-dependent, and NEDDylation pathway-dependent manner.
Storage Conditions
-20°C
Notes
For research use only.

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