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EGFR-IN-152

CAT: 0013-GTR19274752-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274752-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-152 (compound D4) is a potent inhibitor of the EGFR tyrosine kinase and exhibits significant inhibitory activity against the EGFRL858R/T790M/C797S mutations (IC50= 40 nM) . It induces cell cycle arrest at the G0/G1 phase and apoptosis, thereby hindering the clonogenic growth and proliferation of non-small cell lung cancer (NSCLC) cells. EGFR-IN-152 is applicable for NSCLC research.
CAS Number
2463197-87-5
Smiles
N (C=1N (C=2C (N1) =CN=C (NC3=CC=C (C=C3) N4CCN (C) CC4) N2) [C@@H]5CN (S (=O) (=O) C6CC6) CC5) C7=CC=CC=C7
Molecular Formula
C29H35N9O2S
Molecular Weight
573.72
Storage Conditions
-20°C
Notes
For research use only.

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