Antimalarial agent 52

CAT: 0013-GTR19273209-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19273209-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Antimalarial agent 52 is an orally effective synthetic inhibitor of malaria pigment (β-hematin), with an IC50 of 6.6 μM. In vitro, it exhibits antimalarial activity against Plasmodium falciparum strains Pf3D7 and PfDd2, and Plasmodium knowlesi, with IC50 values of 6.1, 6.4, and 3.3 nM, respectively. It remains potent against multidrug-resistant strains and demonstrates significant efficacy in a Plasmodium berghei (P. berghei) mouse model.

Storage Conditions

-20°C

Notes

For research use only.

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