Products for Research Use Only

PROTAC PDE4 degrader-1

CAT: 0013-GTR19263670-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263670-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACPDE4 degrader-1 (Compound 9m) is an orally active, selective PDEC4 PROTAC degrader with a DC50 of 41.98 μM. It effectively inhibits the secretion of pro-inflammatory cytokines, such as TNF-α and IL-6, and significantly reduces pulmonary inflammation in a mouse model of LPS-induced acute lung injury (ALI) .
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.