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WZH-15-125

CAT: 0013-GTR19263441-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263441-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WZH-15-125 is a potent ALK inhibitor capable of overcoming resistance, particularly with complex ALK mutations. It exhibits an IC50 of 101.7 nM against the highly recalcitrant Lorlatinib-resistant G1202R/L1196M mutation. Additionally, WZH-15-125 can serve as a PROTAC target protein ligand for synthesizing PROTACWZH-17-002. This compound is applicable in non-small cell lung cancer research.
CAS Number
2845188-22-7
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=S (=O) (N (C1=C2OCCOC2=CC=C1NC3=NC (=NC=C3Br) NC=4C=C (C (=CC4OC) N5CCC (N6CCN (C) CC6) CC5) CC) C) C
Molecular Formula
C33H45BrN8O5S
Molecular Weight
745.73
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
HY-174314WZH-15-125
T211075-01WZH-17-002
9800U04TEST TUBES: WITH RIM 15 X 125 MM
9820U04TEST TUBES: W/O RIM 15 X 125 MM
226857CA 125 (Cancer Antigen 125, Carbohydrate Antigen 125, CA-125) discontinued
226857-HRPCA 125 (Cancer Antigen 125, Carbohydrate Antigen 125, CA-125) (HRP) discontinued
226857-FITCCA 125 (Cancer Antigen 125, Carbohydrate Antigen 125, CA-125) (FITC) discontinued
226857-BiotinCA 125 (Cancer Antigen 125, Carbohydrate Antigen 125, CA-125) (Biotin) discontinued
226857-PECA 125 (Cancer Antigen 125, Carbohydrate Antigen 125, CA-125) (PE) discontinued
226857-APCCA 125 (Cancer Antigen 125, Carbohydrate Antigen 125, CA-125) (APC) discontinued

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