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EGFR-IN-125

CAT: 0013-GTR19250219-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250219-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-125 (example 37) is a highly potent small molecule inhibitor of EGFR, demonstrating sub-nanomolar IC50 values against key mutant forms including the triple-mutant EGFR (d746-750/T790M/C797S) (<0.3 nM) and wild-type EGFR (0.92 nM) . This compound is a valuable research tool for investigating resistance mechanisms and conducting in vitro studies in non-small cell lung cancer models.
CAS Number
2472802-77-8
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C (NC12CCC (N3C (C#C) =C (C=4C=NC=5C=CC=CC5C4) C=6C (=NC=NC63) N) (CC1) C2) C7=NC=C (N=C7) C
Molecular Formula
C30H26N8O
Molecular Weight
514.58
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
T204450-01EGFR-IN-125
226857CA 125 (Cancer Antigen 125, Carbohydrate Antigen 125, CA-125) discontinued
226857-HRPCA 125 (Cancer Antigen 125, Carbohydrate Antigen 125, CA-125) (HRP) discontinued
226857-FITCCA 125 (Cancer Antigen 125, Carbohydrate Antigen 125, CA-125) (FITC) discontinued
226857-BiotinCA 125 (Cancer Antigen 125, Carbohydrate Antigen 125, CA-125) (Biotin) discontinued
226857-PECA 125 (Cancer Antigen 125, Carbohydrate Antigen 125, CA-125) (PE) discontinued
226857-APCCA 125 (Cancer Antigen 125, Carbohydrate Antigen 125, CA-125) (APC) discontinued
226857-APCA 125 (Cancer Antigen 125, Carbohydrate Antigen 125, CA-125) (AP) discontinued
553388Cancer Antigen 125 (CA-125)
367315CA 125 (MUC16, Cancer Antigen 125, Carbohydrate Antigen 125)

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