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PROTAC ERK5 degrader-1

CAT: 0013-GTR19263316-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263316-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACERK5 degrader-1 (compound 2) is a bifunctional ERK5 PROTAC degrader. It induces the degradation of ERK5 in MOLT-4 cells via a VHL-mediated proteasome pathway. PROTACERK5 degrader-1 is useful for studying diseases or disorders characterized by abnormal ERK5 activity.
CAS Number
2919963-24-7
Field of Research
Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Smiles
C (=O) (N1CCC (C=2C3=C (C=C (C=C3) N4CCN (CCCCCC (N[C@H] (C (=O) N5[C@H] (C (N[C@@H] (C) C6=CC=C (C=C6) C7=C (C) N=CS7) =O) C[C@@H] (O) C5) C (C) (C) C) =O) CC4) N=CN2) CC1) C8=C (N) C=C (OC (F) (F) F) C=C8
Molecular Formula
C54H67F3N10O6S
Molecular Weight
1041.23
Storage Conditions
-20°C
Notes
For research use only.

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