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Antitumor agent-170

CAT: 0013-GTR19262849-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262849-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antitumor agent-170 (Compound C6) inhibits PD-1/PD-L1 interaction and PARP7 with IC50 values of 0.342 μM and 7.05 nM, respectively. It shows high affinity for human PD-L1, with a Ki of 9.31 nM, and can restore T cell function while increasing IFN-γ secretion. In mouse models, Antitumor agent-170 exhibits antitumor effects against melanoma and demonstrates favorable pharmacokinetic properties.
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology
Molecular Formula
C59H69ClF3N11O9
Storage Conditions
-20°C
Notes
For research use only.

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