Products for Research Use Only

BuChE-IN-11

CAT: 0013-GTR19262767-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262767-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BuChE-IN-11 (Compound 3b-1) is a selective inhibitor of BuChE with an IC50 of 0.44 μM for hBuChE. The compound demonstrates high brain-blood barrier permeability and possesses free radical scavenging capabilities, indicating significant antioxidant activity. BuChE-IN-11 interacts with the choline binding site, the acyl binding site, and the peripheral anionic site, showing submicromolar inhibitory activity against BuChE and preventing the self-aggregation of β-amyloid protein (Aβ) . This compound holds promise for research in the field of Alzheimer's disease.
Field of Research
Neuroscience
Molecular Formula
C28H27FN4O2
Storage Conditions
-20°C
Notes
For research use only.

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