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WP9QY (TFA)

CAT: 0804-HY-P2612A-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-P2612A-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WP9QY, TNF-a Antagonist, TNF-a Antagonist is a biological active peptide. (This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.)
UNSPSC
12352209
Target
TNF Receptor
Type
Peptides
Related Pathways
Apoptosis
Field of Research
Others; Cancer
Assay Protocol
https://www.medchemexpress.com/wp9qy-tfa.html
Purity
99.44
Solubility
DMSO : 7.14 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
O=C(N[C@H](C(N[C@H](C(N[C@H](C(N1)=O)CC(C=C2)=CC=C2O)=O)CCC(N)=O)=O)CO)[C@@H](NC([C@H](CSSC[C@H](NC([C@@H]1CC(C)C)=O)C(N[C@H](C(O)=O)CC(C=C3)=CC=C3O)=O)NC([C@@H](N)CC(C=C4)=CC=C4O)=O)=O)CC5=CNC6=CC=CC=C56.OC(C(F)(F)F)=O
Molecular Formula
C60H72F3N11O17S2
Molecular Weight
1340.40
References & Citations
[1]Lin CC, et al. Functional PEG-peptide hydrogels to modulate local inflammation induced by the pro-inflammatory cytokine TNFalpha. Biomaterials. 2009 Oct;30 (28) :4907-14.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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